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The 3rd Musculoskeletal ARCTCIBE and SydMSK Combined Online Workshop
About this Event
The combined workshop: Advancing clinical outcomes with computational technologies is jointly hosted by ARC Training Centre for Innovative Bioengineering and Sydney Musculoskeletal Bone and Joint Health Alliance. Bringing together scientists, engineers, clinicians, industry, early career researchers and students, and driven by imminent clinical needs in musculoskeletal health, this event will be an idea incubator for new biomedical engineering solutions and health technologies. Over an interactive half day program, the event will feature focus talks on the advancements of computational technologies, including emerging topics in Artificial Intelligence, Data Science, Ethics, and Advanced Visualisation.There will be breakout group discussions and one-on-one interactions to exchange ideas across disciplines.
Prof. Jinyan Li
Prof. Jinyan Li is a Professor of Data Science and Program Leader of Bioinformatics at the Data Science Institute, Faculty of Engineering & IT, University of Technology Sydney, Australia. He has been actively working on data mining and bioinformatics for 20 years. He has published 240 papers, including 130 papers in prestigious journals of data mining, machine learning, and computational biology. He is widely known for his pioneering research on the theories and algorithms of Emerging Patterns (EPs). One of these papers has received 1300 Google Scholar citations. Jinyan has a Bachelor degree of Science (Applied Mathematics) from National University of Defense Technology (China), a Master degree of Engineering (Computer Engineering) from Hebei University of Technology (China), and a PhD degree (Computer Science) from the University of Melbourne (Australia). More details of his research can be found at http://www.uts.edu.au/staff/jinyan.li
A/Prof. David Parker
Associate Professor Parker is an orthopaedic surgeon specialising exclusively in surgery of the knee. He completed his orthopaedic training in Sydney, followed by subspecialty knee surgery training in Canada. He has now been in practice in Sydney for 15 years and is nationally and internationally recognised as an expert in the field of knee surgery.
He is regularly invited to speak at international conferences, and is the president of the Asia Pacific Knee Arthroscopy and Sports Medicine Society. He is also Assist. Secretary of the International Society for Arthroscopy Knee Surgery and Orthopaedic Sports Medicine. He is regularly involved in teaching and is an Associate Professor at the University of Sydney, and has a strong interest in clinical research, having established the Sydney Orthopaedic Research Institute.
A/Prof Parker has special interest and expertise in knee replacement surgery, sports injuries of the knee, ligament reconstruction and knee realignment surgery.
A/Prof Parker also has a keen interest in nonsurgical management of knee arthritis, for those patients for whom surgery would not be helpful, and has established the Sydney Intensive Knee Clinic to manage this optimally.
A/Prof Parker has a goal of optimising the management for each patient, using an evidence based approach to achieve the best outcome for every patient by careful consultation, informed discussion, expert surgical management, and thorough postoperative care.
A/Prof. Vasikaran Naganathan
Associate Professor
Medicine, Concord Clinical School
Centre for Education and Research on Ageing (CRGH)
Prof. Lyn March
Professor Lyn March is the Ligins Professor of Rheumatology and Musculoskeletal Epidemiology at Sydney Faculty of Medicine and Health and Head of the Department of Rheumatology at Royal North Shore. She is on the Executive committees of SydMSK, GMUSC and OMERACT. She was the in- augural Co-Chair of the NSW ACI MSK Network that launched the MSK Models of Care. In her Keynote: Evidence into Practice she will take you on the Osteoporosis Re-fracture Prevention Journey.
Dr. Craig Willers
Dr Craig Willers is the National Director of the Australian Arthritis and Autoimmune Biobank Collaborative (A3BC), University of Sydney. Since completing his PhD in orthopaedic tissue engineering, he has worked in health and medical research (mainly musculoskeletal) within university, healthcare, industry, charity and government (NSW Health).His core expertise and interest are large scale, integrated data/informatics and biobanking projects that facilitate collaboration and develop more holistic data models for innovative discovery and efficient evidence-based advances in both patient and population health.
Dr. Kayla Cornett
Dr Kayla Cornett PhD, is a NIH funded postdoctoral research fellow at the University of Sydney and Children’s Hospital at Westmead. She is an expert in clinical outcome measurement for pediatric neuromuscular diseases. As an early career researcher Dr Cornett has over 20 publications including a seminal report published in the Annals of Neurology focusing on the natural history of Charcot-Marie-Tooth disease during childhood. She collaborates with leading researchers in Charcot-Marie-Tooth disease and Spinal Muscular Atrophy internationally with her research focussing on reliable and sensitive assessment of function in children with neuromuscular diseases
Dr. Vi Khanh Truong
Dr. Vi Khanh Truong is an RMIT Vice Chancellor’s Postdoctoral Research Fellow and Fulbright Scholar. Dr. Truong obtained his Ph.D. in Nanobiotechnology in 2012 from Swinburne University of Technology, Australia. He held industrial research positions with the CRC for Polymers and the ARC Steel Research Hub. In these positions, he has designed innovative antimicrobial coatings. In his current research, he further investigates the interactions between microbial cellular structures and nanomaterials to understand “antimicrobial resistance” and develop “next‐generation antimicrobial strategies”.
Prof. Hala Zreiqat
Hala Zreiqat AM is Professor of Biomedical Engineering, a 2016-2017 Radcliffe Fellow at Harvard University, a National Health and Medical Research Council Senior Research Fellow, Director of the ARC Training Centre for Innovative BioEngineering and is Head of the Biomaterials and Tissue Engineering Research Unit in the Faculty of Engineering at the University of Sydney. She is also an Honorary Professor at Shanghai JiaoTong University (2013-2019). Her group consists of multidisciplinary team of researchers including engineers, cell and molecular biologists and clinicians. Her lab works on the development of novel engineered materials and 3D printed platforms for regenerative medicine, particularly in the fields of orthopaedics, dental and maxillofacial applications. In addition, her group is interested in the development of novel nanospheres for growth factors, drug and cell delivery as well as novel injectable materials. She has over 100 peer-reviewed publications. Her pioneering development of innovative biomaterials for tissue regeneration has led to one awarded (US) and 6 provisional patents, 5 as a lead inventor, and several collaborations with inter/national industry partners. She is regularly invited to give keynote and plenary presentations at major international and national conferences. She has organized / chaired a number of major international conferences/ symposia / workshops. She is the immediate past president of the Australian and New Zealand Orthopaedic research Society (2010-2012). She is the founder and chair of the Alliance for Design and Application in Tissue Engineering and the IDEAL Society network. Amongst her awards are: Eureka Prize for Innovative Use of Technology (2019); Payne-Scott Professional Distinction (2019); Member of the Order of Australia 2019; One of the 10 of Australia’s most influential women in engineering, Create magazine (2019);The King Abdullah II Order of Distinction of the Second Class – the highest civilian honor bestowed by the King of Jordan (2018); Leopold Dintenfass Memorial Award, for Excellence in Research (2012) and the University of Sydney Engineering Deans Research Award (2009).
Prof. Qing Li
Professor Qing Li obtained his PhD degree from the University of Sydney in 2000. He received postdoc training from Cornell University, NY, USA 2000 – 2001. He was a recipient of an Australian Research Council (ARC) Australian Postdoctoral (APD) Research Fellowship in 2001 (55 awarded nationwide). Dr Qing Li was a senior lecturer in School of Engineering, James Cook University, Townsville, Australia from 2004 to 2006. He returned to Sydney by taking up a Sesqui senior lectureship in 2006, where he was promoted to Associate Professor in 2010 and Professor in 2014. Prior to his academic appointment in Sydney, Dr Qing Li was a recipient of an Australian Academy of Science (AAS) international award to visit the University of Michigan, Ann Arbor, USA in 2006. Professor Qing Li is now an ARC Future Fellow (2013-2017) in the School of Aerospace, Mechanical and Mechatronic Engineering, at the University of Sydney.
Prof. Alistair McEwan
Professor Alistair McEwan received his PhD from the University of Oxford in 2005. He is currently Ainsworth Chair of Technology and Innovation within the School of Electrical and Information Engineering conducting research into bioelectronics, the electrical and optical properties of tissue and disabilities such as cerebral palsy. He works closely with clinicians from a number of hospitals in Sydney, including the Royal Prince Alfred Hospital, Westmead Hospital, Royal North Shore and Nepean Hospital. His research focuses on using signal processing, electronics and modelling to understand the effects of the impedance of tissue as a biomarker in neurology, cardiology, musculoskeletal tissue and the effect on neuromodulation.
A/Prof. Jinman Kim
Associate Professor Jinman Kim received his PhD in Computer Science from the University of Sydney in 2005. He is currently the Director of the Visual TeleHealth Lab, the Biomedical & Multimedia Information Technology (BMIT) Research Group , School of Computer Science, Faculty of Engineering and Information Technologies, University of Sydney. As an active key member of the BMIT Research Group, he is in charge of a research commercialisation and industry links. He has produced a number of impact publications, including IEEE Transactions, Medical Image Analysis, etc., and received several prestigious external completive grants, including the ARC Discovery and Linkage grants. He is also a Theme Leader in the Faculty’s Institute of Biomedical Engineering and Technologies (BMET).
The 2nd Musculoskeletal ARCTCIBE and SydMSK Combined Online Workshop
About this Event
The 2nd Musculoskeletal ARCTCIBE and SydMSK Combined Online Workshop is hosted by ARC Training Centre for Innovative Bioengineering in coordination with Sydney Musculoskeletal Bone and Joint Health Alliance.
It will bring together clinicians from the Musculoskeletal discipline with biomedical engineers and MSK experts from the University of Sydney. ARC TRAINING CENTRE FOR INNOVATIVE BIOENGINEERING builds links between Engineering, Science, Medicine and Industry.
This half-day meeting will provide an opportunity to the Musculoskeletal clinicians to present clinical issues they would like to solve using technologies to be developed by the Biomedical engineers. There would be an opportunity for one on one interaction and breakout sessions to discuss problems and their solutions. The Centre has strong links to industry (orthopaedic companies) who would be potential partners for any discoveries we may have.
WORKSHOP PRESENTATIONS
Welcome by Prof. David Hunter
Speaker: Prof. Zsolt Balogh
Topic: Segmental Bone Defects in Polytrauma (induced membrane technique for infected non-unions)
Speaker: A/Prof. Rory Clifton Bligh
Topic: Bone health in spinal cord injury–challenges and opportunities
Speaker: Prof. Vasi Naganathan
Topic: Things to think about when developing technology for older people
(Apologies from the organisers: the talk was interrupted several times by internet hackers. )
Speaker: A/Prof. David Parker
Topic: Achieving greater precision in knee reconstruction surgery
Speaker: Prof. David Hunter
Topic: Targeting focal structural abnormalities in osteoarthritis
Speakers: Prof. Lyn March and Dr. Craig Willers
Topic: Integrating research and clinical practice – can we make IT systems and analytics work?
Speaker: Dr Kayla Cornett
Topic: Measuring real-world gait and function in paediatric neuromuscular diseases
Speaker: Prof. Hala Zreiqat
Topic: Solving Musculoskeletal problems
Speaker: Prof. Alistair McEwan
Topic: Electroceutical sensors and stimulation in MSK
Speaker: Prof. Qing Li
Topic: Computational modelling and prosthetic design for mandibular reconstruction
Speaker: A/Prof. Jinman Kim
Topic: Deep learning for musculoskeletal image analysis and visualisation
SPEAKERS
Prof. David Hunter
Professor Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis (OA). He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney and the Royal North Shore Hospital. He is ranked as the worlds leading expert in osteoarthritis on Expertscape.com since 2014. He is on the editorial board for Arthritis and Rheumatology, Osteoarthritis and Cartilage, Arthritis Care and Research and part of the review committee for OA for the American College of Rheumatology, EULAR and OARSI scientific meetings. Dr Hunter has over 450 peer reviewed publications in international journals, numerous book chapters, is the section editor for UpToDate Osteoarthritis and has co-authored a number of books, including books on self management strategies for the lay public.
Prof. Zsolt Balogh
Professor Balogh is the Discipline Head of Traumatology and Surgery and leads the Traumatology Research Group at the University of Newcastle. He is also the Director of Trauma Surgery at the John Hunter Hospital and Hunter New England Local Health District. Apart from a teacher and researcher, he is an active trauma and orthopaedic surgeon with a major interest in complex polytrauma patients and pelvic and acetabulum fracture patients. As the Discipline Head of Traumatology, Professor Balogh is responsible for the Trauma curriculum at the University of Newcastle, which has formal components in years 1,3,4 and 5 in the Medical School. His research covers many areas of trauma care such as orthopaedic trauma, torso trauma and postinjury critical care. He collaborates with academic trauma centres and Universities in Europe, United States and Australia. Professor Balogh supervises the Traumatology PhD program at The University of Newcastle and clinical and research fellowship programs at the John Hunter Hospital.
A/Prof. Roderick Clifton-Bligh
A/Prof Roderick Clifton-Bligh is Head of the Department of Endocrinology at Royal North Shore Hospital, and conjoint associate professor in Medicine at the University of Sydney. He completed a PhD in the genetics of thyroid disorders at the University of Cambridge. He now supervises dual research groups, one of which focuses on the genetics of endocrine neoplasms, and the other on metabolic bone disease.
A/Prof. David Parker
Associate Professor Parker is an orthopaedic surgeon specialising exclusively in surgery of the knee. He completed his orthopaedic training in Sydney, followed by subspecialty knee surgery training in Canada. He has now been in practice in Sydney for 15 years and is nationally and internationally recognised as an expert in the field of knee surgery.
He is regularly invited to speak at international conferences, and is the president of the Asia Pacific Knee Arthroscopy and Sports Medicine Society. He is also Assist. Secretary of the International Society for Arthroscopy Knee Surgery and Orthopaedic Sports Medicine. He is regularly involved in teaching and is an Associate Professor at the University of Sydney, and has a strong interest in clinical research, having established the Sydney Orthopaedic Research Institute.
A/Prof Parker has special interest and expertise in knee replacement surgery, sports injuries of the knee, ligament reconstruction and knee realignment surgery.
A/Prof Parker also has a keen interest in nonsurgical management of knee arthritis, for those patients for whom surgery would not be helpful, and has established the Sydney Intensive Knee Clinic to manage this optimally.
A/Prof Parker has a goal of optimising the management for each patient, using an evidence based approach to achieve the best outcome for every patient by careful consultation, informed discussion, expert surgical management, and thorough postoperative care.
A/Prof. Vasikaran Naganathan
Associate Professor
Medicine, Concord Clinical School
Centre for Education and Research on Ageing (CRGH)
Prof. Lyn March
Professor Lyn March is the Ligins Professor of Rheumatology and Musculoskeletal Epidemiology at Sydney Faculty of Medicine and Health and Head of the Department of Rheumatology at Royal North Shore. She is on the Executive committees of SydMSK, GMUSC and OMERACT. She was the in- augural Co-Chair of the NSW ACI MSK Network that launched the MSK Models of Care. In her Keynote: Evidence into Practice she will take you on the Osteoporosis Re-fracture Prevention Journey.
Dr. Craig Willers
Dr Craig Willers is the National Director of the Australian Arthritis and Autoimmune Biobank Collaborative (A3BC), University of Sydney. Since completing his PhD in orthopaedic tissue engineering, he has worked in health and medical research (mainly musculoskeletal) within university, healthcare, industry, charity and government (NSW Health).His core expertise and interest are large scale, integrated data/informatics and biobanking projects that facilitate collaboration and develop more holistic data models for innovative discovery and efficient evidence-based advances in both patient and population health.
Dr. Kayla Cornett
Dr Kayla Cornett PhD, is a NIH funded postdoctoral research fellow at the University of Sydney and Children’s Hospital at Westmead. She is an expert in clinical outcome measurement for pediatric neuromuscular diseases. As an early career researcher Dr Cornett has over 20 publications including a seminal report published in the Annals of Neurology focusing on the natural history of Charcot-Marie-Tooth disease during childhood. She collaborates with leading researchers in Charcot-Marie-Tooth disease and Spinal Muscular Atrophy internationally with her research focussing on reliable and sensitive assessment of function in children with neuromuscular diseases
Dr. Vi Khanh Truong
Dr. Vi Khanh Truong is an RMIT Vice Chancellor’s Postdoctoral Research Fellow and Fulbright Scholar. Dr. Truong obtained his Ph.D. in Nanobiotechnology in 2012 from Swinburne University of Technology, Australia. He held industrial research positions with the CRC for Polymers and the ARC Steel Research Hub. In these positions, he has designed innovative antimicrobial coatings. In his current research, he further investigates the interactions between microbial cellular structures and nanomaterials to understand “antimicrobial resistance” and develop “next‐generation antimicrobial strategies”.
Prof. Hala Zreiqat
Hala Zreiqat AM is Professor of Biomedical Engineering, a 2016-2017 Radcliffe Fellow at Harvard University, a National Health and Medical Research Council Senior Research Fellow, Director of the ARC Training Centre for Innovative BioEngineering and is Head of the Biomaterials and Tissue Engineering Research Unit in the Faculty of Engineering at the University of Sydney. She is also an Honorary Professor at Shanghai JiaoTong University (2013-2019). Her group consists of multidisciplinary team of researchers including engineers, cell and molecular biologists and clinicians. Her lab works on the development of novel engineered materials and 3D printed platforms for regenerative medicine, particularly in the fields of orthopaedics, dental and maxillofacial applications. In addition, her group is interested in the development of novel nanospheres for growth factors, drug and cell delivery as well as novel injectable materials. She has over 100 peer-reviewed publications. Her pioneering development of innovative biomaterials for tissue regeneration has led to one awarded (US) and 6 provisional patents, 5 as a lead inventor, and several collaborations with inter/national industry partners. She is regularly invited to give keynote and plenary presentations at major international and national conferences. She has organized / chaired a number of major international conferences/ symposia / workshops. She is the immediate past president of the Australian and New Zealand Orthopaedic research Society (2010-2012). She is the founder and chair of the Alliance for Design and Application in Tissue Engineering and the IDEAL Society network. Amongst her awards are: Eureka Prize for Innovative Use of Technology (2019); Payne-Scott Professional Distinction (2019); Member of the Order of Australia 2019; One of the 10 of Australia’s most influential women in engineering, Create magazine (2019);The King Abdullah II Order of Distinction of the Second Class – the highest civilian honor bestowed by the King of Jordan (2018); Leopold Dintenfass Memorial Award, for Excellence in Research (2012) and the University of Sydney Engineering Deans Research Award (2009).
Prof. Qing Li
Professor Qing Li obtained his PhD degree from the University of Sydney in 2000. He received postdoc training from Cornell University, NY, USA 2000 – 2001. He was a recipient of an Australian Research Council (ARC) Australian Postdoctoral (APD) Research Fellowship in 2001 (55 awarded nationwide). Dr Qing Li was a senior lecturer in School of Engineering, James Cook University, Townsville, Australia from 2004 to 2006. He returned to Sydney by taking up a Sesqui senior lectureship in 2006, where he was promoted to Associate Professor in 2010 and Professor in 2014. Prior to his academic appointment in Sydney, Dr Qing Li was a recipient of an Australian Academy of Science (AAS) international award to visit the University of Michigan, Ann Arbor, USA in 2006. Professor Qing Li is now an ARC Future Fellow (2013-2017) in the School of Aerospace, Mechanical and Mechatronic Engineering, at the University of Sydney.
Prof. Alistair McEwan
Professor Alistair McEwan received his PhD from the University of Oxford in 2005. He is currently Ainsworth Chair of Technology and Innovation within the School of Electrical and Information Engineering conducting research into bioelectronics, the electrical and optical properties of tissue and disabilities such as cerebral palsy. He works closely with clinicians from a number of hospitals in Sydney, including the Royal Prince Alfred Hospital, Westmead Hospital, Royal North Shore and Nepean Hospital. His research focuses on using signal processing, electronics and modelling to understand the effects of the impedance of tissue as a biomarker in neurology, cardiology, musculoskeletal tissue and the effect on neuromodulation.
A/Prof. Jinman Kim
Associate Professor Jinman Kim received his PhD in Computer Science from the University of Sydney in 2005. He is currently the Director of the Visual TeleHealth Lab, the Biomedical & Multimedia Information Technology (BMIT) Research Group , School of Computer Science, Faculty of Engineering and Information Technologies, University of Sydney. As an active key member of the BMIT Research Group, he is in charge of a research commercialisation and industry links. He has produced a number of impact publications, including IEEE Transactions, Medical Image Analysis, etc., and received several prestigious external completive grants, including the ARC Discovery and Linkage grants. He is also a Theme Leader in the Faculty’s Institute of Biomedical Engineering and Technologies (BMET).
The Board
2016 Tissue Engineering Symposium Photo Album
2008 Tissue Engineering Symposium Supporters
2008 Tissue Engineering Symposium Photo Album
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2010 Symposium Speakers’ Profile
Prof Dennis E. Discher
Dennis E. Discher is Professor at the University of Pennsylvania in the School of Engineering and Applied Science and in Graduate Groups in Cell & Molecular Biology and Physics. He received a Ph.D. from the University of California, Berkeley in 1993 for studies in cell and molecular biophysics, and was a US National Science Foundation International Fellow at the University of British Columbia until 1996.
He has coauthored more than 150 publications with over 7000 citations that range in topic from matrix effects on stem cells and biochemical physics of protein folding to self-assembling polymers applied to disease, with papers appearing in Cell, Science, Journal of Cell Biology, Nature Materials, and Nature Physics. Honors and Service include a Presidential Early Career Award for Scientists and Engineers from the US- National Science Foundation, the Friedrich Wilhelm Bessel Award from the Humboldt Foundation of Germany, and membership on the editorial board for Science.
Prof John E. J. RASKO
BSc (Med), MBBS (Hons), PhD, MAICD, FRCPA, FRACP
Professor Rasko is a Haematologist who directs Cell and Molecular Therapies at Royal Prince Alfred Hospital and heads the Gene and Stem Cell Therapy Program at the Centenary Institute, University of Sydney. His was the first formal appointment in clinical gene therapy in Australia.
Professor Rasko is a past President of the Australasian Gene Therapy Society, Chairs the International Committee of the American Society of Gene and Cell Therapy and is Vice President of the International Society for Cellular Therapy. He is a member of the editorial boards of Pathology, Human Gene Therapy and The Journal of Gene Medicine. He serves on Hospital, philanthropic, state and national bodies including Chair of the Gene Technology Technical Advisory Committee of the federal Office of the Gene Technology Regulator.
Professor Rasko has a productive track record in gene therapy, experimental haematology and cell biology. His research has been successful in uncovering new mechanisms of leukemia, understanding blood hormones and their mechanisms of action, and clinical trials of new biological therapies for cancer and bleeding disorders. He has authored approximately 100 publications including a book published by Cambridge University Press on the ethics of inheritable genetic modification. In landmark papers in Nature Medicine in 2006 and 2007, with collaborators in the USA he reported the short-term clinical success and immunology of AAV-mediated liver-directed gene therapy for the treatment of haemophilia.
A/ Professor Celeste M. Nelson
Assistant Professor of Chemical & Biological Engineering, Princeton University
Dr. Celeste Nelson did her PhD in Biomedical Engineering at the Johns Hopkins University School of Medicine, studying intercellular-mediated mechanotransduction. She joined the Chemical & Biological Engineering department at Princeton University in 2007 after completing postdoctoral research with Mina Bissell at Lawrence Berkeley National Laboratory, where she worked on mammary branching morphogenesis. Dr. Nelson’s group is highly interdisciplinary and focuses on pattern formation during normal and abnormal development of the mammary gland and lung.
A/Professor Heiko Methe
Heiko Methe is currently an interventional cardiologist at the University Hospital Grosshadern and Associate Professor at the School of Medicine, Ludwig-Maximilians-University in Munich, Germany. In 1998 he obtained his medical degree at the Georg-August University Göttingen, Germany. After a post-doctoral research sabbatical at The Scripps Research Institute in LaJolla, California he spent 2.5 years at the Harvard-MIT Biomedical Engineering Center at the Massachusetts Institute of Technology, Cambridge, Massachusetts.
His research focus is on the potential of endothelial tissue engineered constructs to influence vascular repair processes without endangering a host immune response. Heiko Methe currently is a research affiliate with the Biomedical Engineering Center. After returning to Munich he is now involved in both clinical practice and laboratory research. Heiko Methe received the Daniel Steinberg New Investigator Award in Arteriosclerosis/Lipoproteins by the American Heart Association.
Prof Gordana Vunjak-Novakovic
Gordana Vunjak-Novakovic is a Professor of Biomedical Engineering at Columbia University, where she directs the Laboratory for Stem Cells and Tissue Engineering, the Bioreactor Core of the NIH Tissue Engineering Resource Center, and the Stem Cell Imaging Core. Her lab is working on engineering of human tissues, for use in regenerative medicine and stem cell research. Gordana published 2 books, 45 book chapters, 210 peer-reviewed articles and 34 patents.
She is a frequent advisor to governmental organizations on tissue engineering and regenerative medicine, and the chair of her NIH study section. In 2002, she was elected a Fellow of the American Institute for Medical and Biological Engineering. In 2007, she gave the Director’ lecture at the NIH, as the first woman engineer to receive this distinction.
In 2008, she was inducted into the Women in Technology International Hall of Fame “for developing biological substitutes to restore, maintain or improve tissue function”. In 2009, she was elected to the New York Academy of Sciences. In 2010, she received the Clemson Award of the Biomaterials Society “for contributions to literature”. Her talk is on engineering human tissues (such as heart and bone), by an integrated use of biomaterial scaffolds and bioreactors.
Professor Jürgen Götz
Professor Jürgen Götz is an internationally renowned expert in transgenic mouse models of Alzheimer’s disease (AD). He generated the first tau transgenic mouse model with an early AD phenotype (EMBO J 1995).
Together with Dr. Hutton, he published the first mouse model with NFT formation (JBC 2001a). He provided long-sought evidence for the amyloid cascade hypothesis by combining a transgenic and a transplantation approach (Science 2001). This highly cited work was accompanied by an Editorial in the same issue of Science, and selected as 2001 Milestone Paper by the Alzheimer Research Forum (alzforum.org).
Jürgen Götz further provided a role for FGF5 in the hair growth cycle (Cell 1994), worked on prions (Cell 1998), and showed that the catalytic subunit of PP2A is essential for development (PNAS 1998) and that PP2A is a key enzyme in tau phosphorylation (JBC 2001b, AmJPathol 2003). He established the first in vitro model of Aß-induced tau filament formation (JBC 2003). Using transcriptomics and proteomics he provided evidence for mitochondrial dysfunction and a role for glyoxalase I in AD (PNAS 2003, JBC 2005, Proteomics 2006, PNAS 2009). His review articles are highly cited (e.g., BRR 2001, MolPsych 2004, NatRevNeurosci 2008).
Jürgen Götz has been a continuous member of the GRP (Grant Review Panel) of the NHMRC since arriving in Australia in 2005, and a Chair in 2009.In 2005, Jürgen Götz received the BioFirst (NSW) award; and in 2009 he was awarded NSW Scientist of the Year (Category: Biomedical Sciences).
Current research: Jürgen Götz continues to develop new transgenic animal models and to work on pathological functions of tau, with a focus on tau-targeted treatment approaches and on understanding how tau mediates Abeta toxicity. Another major interest is the commonality of type 2 diabetes and AD and what determines selective vulnerability in AD. In addition to primary neuronal cultures, C. elegans has been established as a model organism in the laboratory.
Recent publications: Rhein V et al (2009) Aß and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer’s disease mice, PNAS 106: 20057 [Highlighted in Nat Rev Neurosci Jan 2010] • Ittner LM et al (2008) Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia, PNAS 105: 15997 • Götz J & Ittner LM (2008) Animal models of Alzheimer’s disease and frontotemporal dementia, Nat Rev Neurosci 9: 532 • Habicht G et al (2007) Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aß protofibrils, PNAS, 104: • Ittner LM et al. (2010) Dendritic Function of Tau Mediates Amyloid-ß Toxicity in Alzheimer’s Disease Mouse Models, Cell, in press
Prof Laura Niklason
Dr. Niklason is a Professor at Yale University in Biomedical Engineering and Anesthesia, and also serves as Vice-Chair for Anesthesia at Yale. She received her PhD in Biophysics from the University of Chicago in 1988, and her MD from the University of Michigan in 1991. She completed her residency training in anesthesia and intensive care unit medicine at the Massachusetts General Hospital in Boston, and completed post-doctoral scientific training at Massachusetts Institute of Technology. From there she went onto a faculty position at Duke University, where she remained from 1998-2005.
During that time, Dr. Niklason founded a biotechnology company (“Humacyte, Inc.”), which is working to bring engineered tissue replacements to patients. In 2006, Niklason moved to Yale University, where she continues to teach, maintain a vigorous scientific laboratory, and works to expand novel cellular therapies.
During her scientific career, Dr. Niklason has become recognized as one of the world’s leading experts in cellular therapies and regenerative medicine. She has become a world-leader in the development of engineered blood vessels for implantation, and other cellular therapies.
Dr. Niklason’s research focuses primarily on regenerative strategies for cardiovascular tissues, and the impact of biomechanical and biochemical signals of tissue differentiation and development. Niklason speaks nationally and internationally on her research, and has received numerous national awards for scientific excellence, and was named one of only 19 “Innovators for the Next Century” by US News and World Report in 2001.
Dr Ross Garrett
Dr. Garrett was born and raised in Sydney, Australia but moved to Adelaide, Australia in 1969 and attended the University of Adelaide there. He obtained a degree in Biochemistry and Organic Chemistry from the University of Adelaide and a Graduate Diploma in Medical Technology from the South Australian Institute of Technology. In 1979 he was employed by the Institute of Medical and Veterinary Science in the Tissue Pathology Department studying the host response to prosthetic wear debris. He then earned his Ph.D. from the University of Adelaide studying metal containing anti-inflammatory drugs.
In 1985 he moved to San Antonio to the University of Texas Science Center at San Antonio to do a Ph.D. fellowship with Dr. Gregory Mundy in bone and cartilage metabolism and then in 1988 joined OsteoSA at its inception. At OsteoSA he was responsible for the identification of bone growth peptides, which would stimulate bone formation.
In 1982 he joined OsteoScreen and in 2001 was made Scientific Director responsible for developing novel assays and approaches for determining the effects of drugs on bone formation.
In 2007 he joined Zimmer as Director of Bone and Drug Device at Zimmer Orthobiologics in Austin Texas. In 2010 he was promoted to Senior Director at Zimmer Orthobiologics.
Dr. Garrett has over 22 years of experience in the area of cell biology and animal models of disease particularly in the field of bone and cartilage research and is adept at identifying novel drugs that work with disease states involving these tissues.
Professor Stephen Hunyor
Stephen Hunyor is a Cardiologist, Professor of Medicine and Director of the Cardiac Technology Centre in the Kolling Institute, University of Sydney at Royal North Shore Hospital.
His principal interest has been in translational research, studying heart damage and repair with a focus on heart failure and its treatment with devices and more recently cellular therapy. His group specialises in “whole heart” response in terms of hemodynamics and cardiac mechanics and energetics. He was Director of the Cooperative Research Centre (CRC) for Cardiac Technology (1992-99) which had a major program in Polymer research and which involved highly effective collaboration between hospitals, Universities, CSIRO and industry.
Professor Hunyor was co-Founder of the North Shore Heart Research Foundation, and a Member of Scientific/Research Advisory Committees to that Foundation and to the Heart Research Institute – Sydney (2007- ), NHMRC Project Grants Review Panel Member (2006- ) and Founder and former Chairman (2005-2007) Heart Assist Technologies Pty Ltd – a “start-up” company to develop a unique implantable heart assist device. He advised government on R&D policy; was Chair of Australia’s 1st “Commercializing Health Innovations Forum” (CHIF ’97), and established the Intellectual Property Unit within the NSW State Health Department. He has published > 180 papers, edited 4 books, and is co-inventor of 4 Patents (USA, China, Australia, Hungary, Canada).
A/Professor Nick Di Girolamo
Associate Professor Nick Di Girolamo is the Director of the Ocular Diseases Research Unit at the University of New South Wales, Australia.He is a Science graduate from the University of Sydney with over 20-years experience in ocular disease that completed his PhD on the “Mechanisms of Tissue Destruction in Inflammatory Eye Disease” in 1998.
His research interests include anterior segment disorders including, uveitis, pterygia, ocular surface neoplasia, and limbal stem cell deficiency (LSCD). He has published over 60 articles in peer reviewed medical journals and has attracted over $3M in funds to support his research program. He is on the editorial board of the Journal of Biomedicine and Biotechnology, a panel member that reviews grants for the National Health & Medical Research Council of Australia and reviewer of manuscripts for over 30 medical journals.
He has a national and international reputation for his knowledge and expertise in matrix metalloproteinase and stem cell biology and was recently awarded ‘Inventor of the Year’ in 2009 by the ABCs New Inventors for developing a novel technique to treat partially blind patients with insufficient corneal stem cells.
Professor Ian E. Alexander
Professor in Paediatrics and Molecular Medicine
BMedSci, MBBS (Hons), PhD, FRACP (paeds), HGSA certified clinical geneticist
Professor Alexander is head of the Gene Therapy Research Unit, a joint initiative of the The Children’s Hospital at Westmead and Children’s Medical Research Institute in Sydney. Within the hospital he also holds appointments as a senior staff specialist and Director of laboratory research.
His training and day-to-day activities in both clinical medicine and laboratory research reflect his interest in translating research progress into improved health outcomes for children. After completing specialty training in paediatrics at Prince of Wales Children’s Hospital he obtained a PhD in Molecular Biology from the Garvan Institute in Sydney before completing clinical genetics training at the Murdoch Institute in Melbourne. He then undertook postdoctoral studies at the Fred Hutchinson Cancer Research Institute in Seattle before returning to Australia to take up his current position. He has since established a translational research program and developed the specialised infrastructure and skill sets required to take promising novel therapies through to clinical application.
His specific expertise and interests include virus-mediated gene transfer with a focus on organs including the liver and bone marrow, both of which have immense promise as targets for the treatment genetic disease in children. His team became the first in Australia to treat a genetic disease (SCID-X1) by gene therapy and are recognised leaders in the establishment of this exciting field in Australia. This is evidenced by his election as the inaugural president of the Australasian Gene Therapy Society in 2001, his recent award of Life membership of the Society and his appointment in 2007 as Chair of the NHMRC Cellular Therapies Advisory Committee.
He was also recently appointed to the position of Professor in Paediatrics and Molecular Medicine at the University of Sydney.
International recognition includes membership of the gene therapy sub-committee of the International Society for Cellular Therapy, Associate Editorship on the Journal of Gene Medicine and membership of the editorial board of Human Gene Therapy.
Professor Peter K M Maitz, AM MD
In 2008 a Chair of Burn Injury and Reconstructive Surgery has been created at the University of Sydney and Peter Maitz is the inaugural Professor.
Professor Maitz is Medical Director of the Burns Unit at Concord Hospital a teaching hospital of the University of Sydney since 2000.
Prof. Maitz is a Plastic Surgeon trained at the University of Vienna/Austria and Harvard University Boston/USA and was awarded the Order of Australia in 2002 for his services to the Bali victims.
Prof. Maitz designed and commissioned the Burns Unit at Concord Hospital, which offers state of the art equipment and techniques for the care of burned patients. His clinical work includes all areas of burn surgery with special interest in burn reconstruction especially in the head and neck area.
In addition to his clinical work Prof. Maitz established the tissue culturing laboratory at Concord Hospital, which supplies cultured skin substitutes to all patients in NSW and serves as a research basis. Main research areas include skin substitutes, cell technology and microsurgery.
Prof. Maitz is the Chairman of the Education Committee of ANZBA and is heavily involved in teaching. The Emergency Management of Severe Burns course (EMSB) is now being administered under Prof Maitz’s leadership in Australia, New Zealand, England, Holland, South Africa, Papua New Guinea, and Bangladesh. Prof. Maitz published extensively in peer reviewed journals and is member of numerous surgical societies worldwide.
Professor Rutledge Ellis-Behnke
Rutledge Ellis-Behnke is a Professor at Heidelberg University Mannheim Faculty of Medicine where he is the Director of the Nanomedicine Translational Think Tank. In addition, he is a Research Affiliate in the Brain and Cognitive Sciences department at the Massachusetts Institute of Technology. Previously he was Associate Director of the Technology Transfer Office and Associate Professor in the Faculty of Medicine at the University of Hong Kong. His primary research interest is using nanotechnology to reconnect the disconnected parts of the brain in order to restore function.
Ellis-Behnke received his PhD from MIT in Neuroscience, BSci from Rutgers University and graduated from Harvard Business School’s International Senior Manager’s Program (AMP/ISMP).
Prior to returning to school to pursue his PhD, Ellis-Behnke held various management positions including Senior Vice President of Huntingdon, a public company for testing and consulting services and Co-founder/CEO in 1995 of one of the first internet companies to do online commerce.
Ellis-Behnke is Associate Editor/Neurology for the journal Nanomedicine: Nanotechnology, Biology and Medicine; member of both the Executive and Scientific Advisory Boards for the Glaucoma Foundation; member of the Executive Board of the Asia Foundation for Cancer Research; member of the China Spinal Cord Clinical Trial Network, Society for Neuroscience, American Chemical Society, Association for Research in Vision and Ophthalmology and Sigma Xi, the scientific research society.
Technology Review named his “Nanohealing” discoveries one of the “Top 10 Emerging Technologies of 2007.” His “Nano Neuro Knitting” and “Immediate Hemostasis” technologies have each been licensed for translation to humans.
In addition to his work in neuroscience and nanomedicine Ellis-Behnke introduced the TabletPC to MIT and the University of Hong Kong as part of the migration to the paperless classroom to deliver all course material and texts to the students digitally.
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2010 Tissue Engineering Symposium Photo Album
Arrival of Chancellor
Speakers and Presentations
Interactions and Networking
